Zaijun Zhang Selected Research

Thymidine Monophosphate (TMP)

1/2021	Tetramethylpyrazine Improves Cognitive Impairment and Modifies the Hippocampal Proteome in Two Mouse Models of Alzheimer's Disease.
1/2019	Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo.
1/2018	A novel Danshensu/tetramethylpyrazine derivative induces vasorelaxation on rat aorta and exerts cardioprotection in dogs.
1/2017	Synthesis and Biological Evaluation of Danshensu and Tetramethylpyrazine Conjugates as Cardioprotective Agents.
12/2016	Potent Protection Against MPP+-Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine.
10/2008	Antioxidative and thrombolytic TMP nitrone for treatment of ischemic stroke.

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Zaijun Zhang Research Topics

Disease

21	Alzheimer Disease (Alzheimer's Disease) 02/2022 - 04/2015
15	Parkinson Disease (Parkinson's Disease) 11/2021 - 08/2012
14	Ischemic Stroke 01/2021 - 10/2008
13	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2021 - 01/2012
10	Stroke (Strokes) 12/2019 - 10/2008
9	Neoplasms (Cancer) 11/2017 - 06/2006
6	Cognitive Dysfunction 07/2021 - 01/2016
5	Mitochondrial Diseases (Mitochondrial Disease) 12/2021 - 01/2017
5	Inflammation (Inflammations) 12/2021 - 06/2015
5	Myocardial Ischemia (Ischemic Heart Diseases) 01/2018 - 09/2013
4	Neuroinflammatory Diseases 12/2021 - 01/2017
3	Amyloid Plaque 01/2020 - 04/2015
3	Cerebral Infarction 01/2018 - 10/2015
2	Lung Neoplasms (Lung Cancer) 04/2022 - 01/2012
2	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2021 - 01/2019
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 07/2020 - 01/2019
2	Colitis 01/2020 - 01/2016
2	Pathologic Processes 01/2020 - 11/2017
2	Intracranial Vasospasm 01/2019 - 01/2019
2	Neuroblastoma 01/2018 - 10/2016
2	Hypoxia (Hypoxemia) 09/2017 - 01/2017
2	Cardiovascular Diseases (Cardiovascular Disease) 09/2017 - 08/2015
2	Myocardial Infarction 09/2017 - 06/2015
2	Leukemia 05/2017 - 12/2015
2	Infarction (Infarctions) 01/2017 - 11/2016
2	Body Weight (Weight, Body) 01/2014 - 10/2010
2	Leukemia L1210 01/2012 - 06/2006
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2021
1	Disease Progression 01/2021
1	Fibrosis (Cirrhosis) 01/2021
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2021
1	Dementia (Dementias) 01/2020
1	Memory Disorders (Memory Loss) 01/2020
1	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2019
1	Brain Injuries (Brain Injury) 01/2019

Drug/Important Bio-Agent (IBA)

18	Neuroprotective AgentsIBA 11/2021 - 10/2008
14	Pharmaceutical PreparationsIBA 07/2021 - 07/2008
13	tetramethylpyrazineIBA 07/2021 - 01/2014
9	Proteins (Proteins, Gene)FDA Link 12/2021 - 02/2015
9	tetramethylpyrazine nitroneIBA 01/2021 - 01/2014
8	Free RadicalsIBA 01/2019 - 10/2008
6	Amyloid (Amyloid Fibrils)IBA 02/2022 - 01/2018
6	Thymidine Monophosphate (TMP)IBA 01/2021 - 10/2008
6	Therapeutic UsesIBA 01/2021 - 01/2014
5	Memantine (Namenda)FDA Link 01/2021 - 01/2017
5	andrographolideIBA 01/2020 - 07/2009
4	N-Methylaspartate (NMDA)IBA 01/2021 - 01/2018
4	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2021 - 01/2018
4	NitratesIBA 01/2021 - 01/2017
4	Ephrin-A5 (AL-1)IBA 01/2020 - 07/2014
4	Biological ProductsIBA 12/2019 - 01/2016
4	3,4-dihydroxyphenyllactic acidIBA 01/2018 - 06/2015
3	FlavonoidsIBA 12/2021 - 08/2012
3	ProteomeIBA 01/2021 - 02/2015
3	CalciumIBA 07/2020 - 01/2014
3	Glutamic Acid (Glutamate)FDA Link 07/2020 - 01/2018
3	CopperIBA 01/2019 - 04/2018
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 11/2017 - 01/2014
3	indirubinIBA 05/2017 - 12/2015
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017 - 06/2015
2	LipopolysaccharidesIBA 12/2021 - 01/2019
2	xanthohumolIBA 12/2021 - 01/2018
2	MelatoninIBA 12/2021 - 09/2020
2	Adenosine Triphosphate (ATP)IBA 12/2021 - 01/2020
2	dauricineIBA 01/2020 - 01/2018
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2020 - 11/2018
2	AlkaloidsIBA 01/2020 - 01/2018
2	1,2,3,4-tetrahydroisoquinolineIBA 01/2020 - 01/2018
2	SynucleinsIBA 01/2020 - 04/2019
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020 - 10/2019
2	Glycogen Synthase (Synthase I)IBA 01/2019 - 01/2017
2	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2019 - 10/2016
2	Donepezil (Aricept)FDA LinkGeneric 01/2019 - 01/2016
2	3- (4- dimethylaminobenzylidene)- 1,3- dihydroindol- 2- oneIBA 11/2017 - 03/2013
2	Monoamine Oxidase (MAO)IBA 11/2017 - 04/2017
2	DT-010IBA 09/2017 - 12/2016
2	chrysinIBA 07/2016 - 07/2015
2	Peptides (Polypeptides)IBA 10/2015 - 02/2015
1	Conditioned Culture MediaIBA 04/2022
1	Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA 02/2022
1	Presenilin-1IBA 02/2022
1	Mitochondrial DNA (mtDNA)IBA 12/2021
1	polydatinIBA 11/2021
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 09/2020
1	Antidepressive Agents (Antidepressants)IBA 09/2020
1	Dextran SulfateIBA 01/2020
1	Nerve Growth Factors (Neurotrophins)IBA 01/2020
1	Ribosomal Proteins (Ribosomal Protein)IBA 01/2020
1	Oxidopamine (6 Hydroxydopamine)IBA 01/2020
1	tau Proteins (tau Protein)IBA 01/2020
1	alpha-SynucleinIBA 10/2019
1	Threonine (L-Threonine)FDA Link 01/2019
1	Protein Isoforms (Isoforms)IBA 01/2019
1	CalcineurinIBA 01/2019
1	Serine (L-Serine)FDA Link 01/2019
1	Amyloid beta-PeptidesIBA 01/2019

Therapy/Procedure

10	Therapeutics 01/2019 - 10/2008
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2021 - 01/2021
1	Denervation 01/2021
1	Microbubbles 01/2020